DNA display of PNA-tagged ligands
نویسنده
چکیده
Over the past decade, several technologies have emerged to access nucleic acid-tagged libraries and select the fittest compound within such libraries. This perspective focuses on recent development with PNA-tagged small molecules displayed on DNA templates for screening purposes and to probe the optimal geometry in multivalent interactions.
منابع مشابه
DNA display of PNA-tagged ligands A versatile strategy to screen libraries and control geometry of multidentate ligands
Over the past decade, several technologies have emerged to access nucleic acid-tagged libraries and select the fittest compound within such libraries. This perspective focuses on recent development with PNA-tagged small molecules displayed on DNA templates for screening purposes and to probe the optimal geometry in multivalent interactions. WINSSINGER, Nicolas. DNA display of PNA-tagged ligands...
متن کاملA versatile strategy to screen libraries and control geometry of multidentate ligands
Over the past decade, several technologies have emerged to access nucleic acid-tagged libraries and select the fittest compound within such libraries. This perspective focuses on recent development with PNA-tagged small molecules displayed on DNA templates for screening purposes and to probe the optimal geometry in multivalent interactions. WINSSINGER, Nicolas. DNA display of PNA-tagged ligands...
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